May 13, 2020

Functional Role of Dietary Intervention to Improve the Outcome of COVID-19: A Hypothesis of Work

Posted by in category: biotech/medical

Hypothetical COVID-19 Treatments.

The virus causes clotting everywhere and widespread epithelial damage. One is tempted to treat it like stroke prophylaxis. Patients clot rather than bleed, almost always. The same thing happens in influenza, also.

The pro-clotting effects of corticosteroids may be a reason why they have not stood out yet. The profound anticlotting treatment necessary to treat patients with ECMO extracorporial oxygenation in COVID-19, might have its own therapeutic value (it’s not just the artificial lung but the heparin they need to put you on it!). The lungs of COVID-19 patients in trouble are not only full of fluid, but macro and micro-emboli. Low molecular weight heparin, given in all ICUs, looks like a good gamble.

Aspirin if not contraindicated. Also even Plavix (clopidagrel) for patients with D-dimer showing.

The w-3 fatty acids in fish oil are anti-inflammatory in ways that inhibit clotting, and have been used against shock lung and other inflammatory lung pathologies. Work on COVID-19 is continuing but all are in the hypothetical pipeline.

Drugs which in theory modulate inflammation and clotting in the right direction would be Ca-blockers (particularly verapamil) and ACE-1 inhibitors (particularly lisinopril). The anticlotting antiinflammatory pentoxiphylline (Trental) looks interesting. Trental decreases inflammasomes along with azithromycin (do not exceed recommended dose!), long of interest in COVID-19. Doxycycline and minocycline have specific antiinflammatory activity synergistic with azithromycin.

Background: On the 31 December 2019, the World Health Organization (WHO) was informed of a cluster of cases of pneumonia of unknown origin detected in Wuhan City, Hubei Province, China. The infection spread first in China and then in the rest of the world, and on the 11th of March, the WHO declared that COVID-19 was a pandemic. Taking into consideration the mortality rate of COVID-19, about 5–7%, and the percentage of positive patients admitted to intensive care units being 9–11%, it should be mandatory to consider and take all necessary measures to contain the COVID-19 infection. Moreover, given the recent evidence in different hospitals suggesting IL-6 and TNF-α inhibitor drugs as a possible therapy for COVID-19, we aimed to highlight that a dietary intervention could be useful to prevent the infection and/or to ameliorate the outcomes during therapy. Considering that the COVID-19 infection can generate a mild or highly acute respiratory syndrome with a consequent release of pro-inflammatory cytokines, including IL-6 and TNF-α, a dietary regimen modification in order to improve the levels of adiponectin could be very useful both to prevent the infection and to take care of patients, improving their outcomes.


Comment — comments are now closed.

  1. Pleyroha says:

    People should know that the proper use of vitamin C is a tested and verified safe, cheap and effective treatment, and prophylactic, against covid-19 — see orthomolecular d ot o r g (click on ‘Library’ and then ‘News Releases’ and read the editions from about February of 2020 on forward)

    A lot of this is based on Nobel laureate Linus Pauling’s pioneering work. HOWEVER.…. everyone should keep the following in mind, especially now with the corona scamdemic going on: there are many bogus voices around who strive to distract the public from (1) the value of vitamin C therapy and (2) the fact that Pauling’s VALID work with vitamin C supplementation has been “falsified” by data distortions and lies, and he as a person (a double Nobel laureate) has been slandered as some deluded idiot by the criminal medical establishment and its countless quackwatch shills, lackeys, ignoramuses, and trolls for decades and it continues today — search for the scholarly report “2 Big Lies: No Vitamin Benefits & Supplements Are Very Dangerous” by Rolf Hefti (a published author of the Orthomolecular Medicine News organization). The same corrupt criminal people (and their uninformed followers) are behind the organized suppression, lies, and half-truths spread about the value of vitamin C therapy against covid-19 — see orthomolecular d ot o r g

    But you can’t discredit the facts with lies. That only exposes and discredits the liars (see citations above).

    The fact that we are dealing with a VERY CRIMINAL OFFICIAL POWER STRUCTURE (the Deep State, governments, official corporate medicine, the mainstream media, paid off scientists, etc) that constantly hoodwinks the unsuspecting public with MANY BIG LIES can easily be recognized by anyone with two working brain cells when reading this one sentence by a former US government official, Paul Craig Roberts, Ph.D., in his article ‘The Cost of Big Pharma’s Covid-19 Vaccine Will Be Paid in Lives and in Billions of Dollars’:

    “A corrupt establishment and media that can sell us 9/11, Saddam Hussein’s weapons of mass destruction, Iranian nukes, Assad’s use of chemical weapons, a Russian invasion of Ukraine, Russiagate and a large number of other lies can also sell us on locking up a successful treatment in the closet while we await a vaccine.”

    But having true knowledge like that is not enough in itself, YOUR BEHAVIOR must reflect the implications of that knowledge.… ESPECIALLY NOW IN THE FACE OF THIS MASSIVE EVIL SCAM. As the American social critic Paul Rosenberg pointed out in his article ‘Nothing Changes As Long As You Obey’:

    “I hear the same complaints about politicians that you do. And while I understand them, the fact is that complaining accomplishes almost nothing. And there is a very simple reason why complaining has no real effect: BECAUSE THE COMPLAINERS KEEP RIGHT ON OBEYING. As long as you obey, the things you complain about will keep on happening.”

    And there are the profound words of Martin Luther King, Jr.:

    “Most people can’t stand up for their convictions, because the majority of people might not be doing it. See, everybody’s not doing it, so it must be wrong. And since everybody is doing it, it must be right. […]. Cowardice asks the question: is it safe? Expediency asks the question: is it politic? Vanity asks the question: is it popular? But conscience asks the question: is it right? And there comes a time when one must take a position that is neither safe, nor politic, nor popular – but one must take it simply because it is right. […]. Human salvation lies in the hands of the creatively maladjusted.”