Dr. Stephen Minger
The BBC reported in UK human embryonic stem cell first that
Human embryonic stem cells have been grown in the UK for the first time, a team at King’s College London announced Wednesday…
Dr Stephen Minger, one of the lead scientists on the King’s project, told the BBC: “The things we’re most interested in are Type 1 diabetes and Parkinson’s disease.
“We already know that putting cells into patients with those diseases works but there’s a significant shortage of transplantable material.
“So our idea is to try to change these cells specifically into cells that make dopamine or cells that make insulin”, he said.
Dr. Stephen Minger is the
Director of the
Stem Cell Biology Laboratory and a Senior Lecturer in
the new Wolfson Centre for Age-Related Disorders at
King’s College London. He
received his BA in Psychology from the
University of Minnesota and his PhD in Pathology (Neurosciences) in
1992 from the
Albert Einstein College of Medicine, where he studied with Professor
Peter Davies, Resnick Professor of Alzheimer’s Disease Research. From
1992–1994, he was a post-doctoral fellow in the laboratory of
Professor Fred Gage,
University of California, San Diego, where he first began to
pursue research in neural stem cell biology. Additional post-doctoral
training was obtained at the
University of Kentucky.
In 1995, Stephen was appointed an Assistant Professor in Neurology at The
University of Kentucky Medical School. He moved his stem cell
research
programme to
Guy’s Hospital, London in 1996 and was appointed a Lecturer in
Biomolecular Sciences at
King’s College London in 1998. Over the last 13
years, his research group has worked with a wide range of somatic stem
cell populations, as well as mouse and human embryonic stem (ES) cells.
In 2002, together with Dr. Susan Pickering and Professor Peter Braude,
Stephen was awarded one of the first two licenses granted by the
Human Fertilisation and Embryology Authority for the derivation of
human ES
cells. His group subsequently generated the first human embryonic stem
cell line in the UK and was one of the first groups to deposit this into
the
UK Stem Cell Bank.
They have gone on to generate three new human ES cell lines,
including one that encodes the most common genetic mutation resulting in
Cystic Fibrosis.
In addition to the derivation of human ES cell lines, the Stem Cell
Biology Laboratory is
focused on the generation of a number of therapeutically relevant human
somatic stem cell
populations from
embryonic stem cells. These include cardiac, vascular,
retinal, and neural
stem/progenitor cell populations, pancreatic
β-cells and
oligodendrocyte
progenitors.
Stephen has established highly productive collaborations with a number
of specialist
groups in many areas of clinical interest throughout the UK, and is one
of the co-organizers of
the
London Regenerative Medicine Network, a grass roots, research-led
organization designed
to stimulate clinical translation of cell- and gene-based therapies
within London.
The UK
Medical Research Council,
Juvenile Diabetes Research Foundation International,
The Wellcome Trust, and
Diabetes UK are some of the many organizations who fund his
research.
Stephen is Senior
Editor of
Regenerative Medicine, a new journal launched January 2006,
focused on
stem cells, tissue engineering, gene therapy and clinical translation of
new emerging biological therapies.
Read his
LinkedIn profile.