Dr. Arthur W. Toga
The National Geographic article First Ever Brain “Atlas” Completed said
Scientists have made a complete “atlas” of the mouse brain, which they hope will spark a new era of insight into how the brain works and what happens when it breaks down.
The Allen Brain Atlas, launched with a hundred million U.S. dollars from Microsoft co-founder Paul Allen, provides an online, three-dimensional map showing where each of more than 21,000 genes is activated in the mouse brain.
“No one has ever done anything like this before,” Arthur Toga, a professor of neurology at the University of California at Los Angeles’s School of Medicine, told National Geographic News.
“It tells us not just what genes are there, but where they are,” added Toga, who is a member of the brain atlas’s scientific advisory panel.
Arthur W. Toga, Ph.D. is
Professor, Department of Neurology,
Director, Laboratory of Neuro Imaging, Department of Neurology, and
Co-Director, Division of Brain Mapping, Neuropsychiatric Institute, all
at the University of
California
at Los Angeles (UCLA). His research is focused on neuroimaging,
mapping brain structure and function, and brain atlasing. He also
studies cerebral metabolism and neurovascular coupling. He was trained
in neuroscience and computer science and has written more than 650
papers, chapters and abstracts, including eight books.
Recruited to
UCLA
in 1987, he formed and directs the
Laboratory of Neuro Imaging. This
100-member laboratory includes graduate students from computer science,
biostatistics and neuroscience. It houses one of the largest computing
facilities of any University of California research laboratory, and is
funded by National Institutes of Health grants as well as industry
partners. He is Director of the Training Program in Neuroimaging,
Co-Director of the Division of Brain Mapping and Founding Editor of the
journal
NeuroImage.
As Principal investigator and
Director of LONI (Laboratory of Neuro-Imaging),
Art has established a new research infrastructure, the Center for
Computational Ecology. The Center provides a framework in which
investigators from mathematical sciences, clinical research, and
computational biology can openly communicate and exchange ideas for the
purpose of developing new computational tools. Advances in the basic
science area include introducing new non-linear algorithms for spatial
normalization, feature extraction and data mining. Each of these
algorithms is then implemented, tested and validated as software tools
and applied in the field of computational neuroscience. The wide range
of collaborative initiatives undertaken at the Laboratory of
Neuro-Imaging (LONI) efficiently disseminates knowledge and tools to
the
community.
Art
edited
Brain Warping and
Three Dimensional Neuroimaging,
coedited
Brain Mapping: The Systems,
Brain Mapping: The Disorders,
Brain Mapping: The Methods, Second Edition, and
Brain Mapping: The Trilogy, 3 Volume Set,
authored
Neuroimage, and
coauthored
The Rhesus Monkey Brain in Stereotaxic
Coordinates,
Genetic influences on brain structure,
A surface-based technique for warping 3-dimensional images of the
brain,
In vivo evidence for post-adolescent brain maturation in frontal and
striatal regions,
and
A Probabilistic Atlas of the Human Brain: Theory and Rationale for
Its
Development The International Consortium for Brain Mapping
(ICBM).
Art earned his B.S. (Magna cum Laude) in Psychology at the
University of Massachusetts in 1974, his
M.S. (cum Laude) in Neurosciences at St. Louis University
in 1976,
and his Ph.D. (cum Laude) in Neurosciences at St. Louis University in
1978.