Andrew Hessel, MSc.
Andrew Hessel,
MSc,
iGEM Program Development,
Alberta
Ingenuity Fund,
is a consulting biologist and author interested in synthetic
biology and open source biology. DNA is a programming
language that scientists have been working to reverse engineer with
increasing success. Synthetic biology allows forward engineering,
permitting scientists to write code de novo and allowing logical, fully
understandable evolution of biological outputs ranging from single
proteins to, eventually, synthetic cells and synthetic
organisms.
Andrew
advocates the use of open source for writing DNA code. In software
development, open source has led to robust code, highly skilled
developer communities, and non-monopolistic pricing — in other
words,
good things for end users. If the same results can be achieved in
genome engineering, open source could potentially create a more
diversified and sustainable biotechnology industry. These ideas are
explored in
Open Sources 2.0, published by O’Reilly.
He earned his MSc. in bacterial genomics from the University of
Calgary
in 1995. He joined the Amgen Institute, a 120 person research facility
located in Toronto, Canada, as a bioinformaticist and manager. Working
as a bridge between the Institute, Amgen Canada, and Amgen Inc.
(Thousand Oaks, CA), he facilitated dozens of advanced research
projects
involving microarrays, genetic sequence analysis, and data mining.
Today, the Institute, no longer affiliated with Amgen, is known as the
Campbell Family Institute for Breast Cancer Research. In 2002, he
cofounded Miikana Therapeutics and helped create the virtual
business model they successfully used. Miikana was sold to Entremed in
December, 2005 for $21 million plus milestones.
Since 2003, Andrew has worked to raise awareness about the potential
benefits of synthetic biology and open source biology. His efforts have
been supported by the University of Oklahoma, the University of
Toronto, MIT, and most recently, the Alberta Ingenuity Fund. His
ongoing
goal is to help create an open source biotechnology company that
specializes in individually personalized cancer therapeutics. He finds
it
amusing that many people think this idea is ludicrous, yet consider $1B
and 10 years to develop a new drug perfectly reasonable. Time will
tell.
Watch his Google Tech Talk
Pimp my Genome! The Mainstreaming of Digital Genetic
Engineering.
Watch his SENS 3 presentation
Synthetic viruses targeting cancer.